Hyperbaric Oxygen Therapy
One supervised session breathing concentrated oxygen in a pressurised chamber: the way to find out how you tolerate HBOT before any course.
Hyperbaric oxygen therapy (HBOT) is an established medical treatment that is now being studied in ageing. The best-known study is a 2020 prospective trial from the Israeli group led by Professor Shai Efrati at Shamir Medical Center and Tel Aviv University (Hachmo Y et al., Aging). Thirty-five healthy adults aged 64 and over had 60 HBOT sessions over 90 days. Telomere length in some immune-cell populations rose by roughly 20-38%, and senescent T-helper cells fell. The study had no control group, and it has not been replicated in a controlled trial. It does not show that HBOT slows ageing.
How HBOT works: you breathe 100% oxygen inside a pressurised chamber at 1.5-2.0 atmospheres absolute (ATA). At sea level, your blood plasma carries only a small amount of dissolved oxygen. Under pressure, Henry's Law means far more oxygen dissolves into plasma, up to 10-15 times the normal amount. This oxygen-rich plasma can reach tissues with poor circulation, inflammation or injury.
Researchers describe a "hyperoxic-hypoxic paradox". Repeated high-oxygen exposure, followed by a return to normal air, appears to switch on some of the same pathways the body uses in response to low oxygen, including hypoxia-inducible factor (HIF-1a), vascular endothelial growth factor (VEGF) and stem cell mobilisation. This is the proposed mechanism behind the changes reported in the 2020 study. It is a hypothesis under study, not settled science.
HBOT is an established treatment for conditions such as decompression sickness, carbon monoxide poisoning, some non-healing wounds and radiation injury. Its use in longevity, brain injury recovery and inflammation is an area of active research, and the evidence there is still early. We do not offer it as an anti-ageing treatment.
At Genoryx, our medical-grade HBOT chamber operates under physician supervision. Single sessions are available for first-time users, with structured 10-session and 40-session courses for goals agreed with your physician. Book a consultation with our longevity physician to decide whether HBOT suits your goals.
Plausible biology and early human data. We tell you what is and is not known. How we grade evidence
What it shows
HBOT is an established treatment for conditions such as decompression sickness, carbon monoxide poisoning and some non-healing wounds.
What it does not show
For recovery and healthy ageing the evidence is early. The telomere finding comes from one uncontrolled study of 35 people using 60 sessions, and has not been repeated in a controlled trial.
Review: trials support HBOT for refractory diabetic wounds and radiation injury; other uses need more study.
One uncontrolled trial of 35 adults aged 64 and over, 60 sessions: telomeres in some immune cells lengthened by more than 20%.
Numbers in brackets point to the studies above. Medical review: a physician who did not write this page checks each line against the source it cites, and checks that nothing reads as a promised result. How we review
A good fit
Talk to us first
Your physician confirms at screening whether this is right for you. If anything above applies, tell us when you book.
Screening
Ears, lungs, medicines and claustrophobia are reviewed before your first session.
Pressurisation
The chamber is pressurised gradually while you equalise your ears, much like the descent on a flight.
The session
You rest and breathe normally while the team monitors you: 60-90 minutes per session (including pressurization and depressurization).
Review
Slow depressurisation, a quick check, then progress is reviewed across the course.
Dr. Asritha, MD Anaesthesia, leads the execution of all IV therapy and HBOT protocols, ensuring clinical-grade safety, dosing accuracy, and emergency preparedness for every session.
Meet the clinical teamNot on current evidence. One small 2020 study of 35 adults aged 64 and over, with no control group, found that 60 HBOT sessions over 90 days were followed by longer telomeres in some immune-cell types and fewer senescent T-helper cells. It has not been replicated in a controlled trial, and it is not evidence that HBOT slows ageing or extends life.
It depends on your goal. A single session shows you how you tolerate the chamber. A 10-session pack is a short course for recovery goals. Our 40-session course is not the 60-session protocol used in the 2020 telomere study, and we do not claim it reproduces those results; 40-session courses have been used in HBOT research for other goals, such as persistent post-concussion symptoms. Your physician will recommend a course for your specific goal.
HBOT is generally well tolerated in a medical facility with screening and supervision. Common effects include temporary ear pressure (like an airplane descent, managed with equalisation techniques) and mild fatigue. Rare side effects include temporary, reversible short-sightedness and, very rarely, oxygen toxicity seizures. Our medical team supervises every session.
Evidence · Established
The fasting blood panel in the 400+ parameter entry assessment: heart, metabolic, hormone, liver, kidney and inflammatory health, read with a physician.
30-45 minutes (blood draw) + 60-minute physician consultation
Evidence · Strong & indicated
A 60-second bioelectrical impedance scan of muscle, fat, visceral fat and body water by body segment, reviewed with a physician.
60 seconds (scan) + 15-minute physician review
Evidence · Established
Dual-energy X-ray absorptiometry, a reference method for measuring fat, lean mass, visceral fat and bone density region by region.
10-15 minutes (scan) + 30-minute physician review
Start with the 400+ parameter entry assessment and a 60-minute physician consultation at either Hyderabad clinic. Open seven days, 11 AM to 9 PM.
Book a consultation