Knowledge Hub
Dr. R. Brahmananda Reddy
7 April 2026

The anti-seed oil argument rests on omega-6:omega-3 ratio imbalance, oxidation from processing, and epidemiological correlation with chronic disease rise.
On Inflammation: A 2025 review concluded linoleic acid from seed oils does not increase chronic disease risk. Controlled trials show no increase in CRP, IL-6, or TNF-alpha with high omega-6 intake.
On Cardiovascular Outcomes: A 2025 cohort found highest plant-based oil intake associated with 16% lower total mortality. The AHA states reducing omega-6 could increase cardiovascular disease risk.
On the Ratio Argument: Stanford Medicine's 2025 review cautioned against focusing on ratios. Absolute omega-3 intake matters more.
Ultra-processed food context (the vehicle, not just the oil), repeated heating generating harmful aldehydes, quality variation between refined and cold-pressed, and displacement of whole foods.
Seed oils in moderation are not harmful. Use extra virgin olive oil as primary oil. Prioritise omega-3 intake over omega-6 restriction. Avoid repeatedly heated oils. Minimise ultra-processed foods. Get your omega-3 index tested.
Use cold-pressed mustard oil, coconut oil, or ghee for cooking, EVOO for salads, and focus on increasing omega-3 through fish, walnuts, and supplementation.
At Genoryx, we measure your omega-3 index and inflammatory markers. Book a consultation and let your biomarkers guide your nutrition strategy.
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UK-trained physician and founder of Genoryx. Writes about longevity medicine, healthspan optimization, and evidence-based wellness.
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