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Iron and red cells

Ferritin, your iron store Serum Ferritin

The protein your body stores iron in.

Also printed asFerritin

What it measures

The protein that holds your reserve iron, so its level reflects how much iron you have banked.

Empties long before haemoglobin falls, which is why low ferritin explains fatigue and hair loss in someone who is not yet anaemic.

Why it matters for how long you stay well

It is the earliest warning of an iron shortage, and in India it also decides whether your three-month sugar average can be trusted, because low iron lifts that number on its own.

How it shows up in daily life

Low stores can leave you tired, breathless and losing hair long before haemoglobin itself drops.

High and low readings

When it reads high

Can rise with inflammation or liver strain, not only with iron overload - read it with hs-CRP.

When it reads low

Your iron reserve is running down, usually before haemoglobin drops.

What moves it

Daily life

  • iron from meat, dal, green leafy vegetables and jaggery
  • vitamin C with meals
  • tea and coffee with meals, which block iron
  • heavy periods
  • blood donation

Medicines known to shift it

  • iron supplements (raise it)
  • PPIs (can lower it by reducing iron absorption)

Listed so a result can be read in context. It is not advice to start, stop or change any medicine; that decision belongs with your physician.

Read it with

Markers that move this one, or that this one moves. One number read alone can mislead.

  • As this rises, Three-month sugar average can be misread because of it

    Low iron stores make red cells live longer, and older cells have had more time to collect sugar. So the three-month average reads high without your sugar having moved.

  • Iron-binding capacityKnown mechanism

    As this rises, Iron-binding capacity falls as it rises

    When stores run low, your body builds more iron carriers to catch whatever arrives. So binding capacity climbs as your stores fall; the two move in opposite directions.

  • Transferrin saturationKnown mechanism

    As this rises, Transferrin saturation moves with it

    Saturation is how full those carriers are. Empty stores mean less iron to load onto them, so saturation falls alongside the stores.

  • As this rises, Haemoglobin rises with it

    Iron is the raw material your body builds haemoglobin from. Stores empty first, and only once they are empty does haemoglobin start to fall.

  • Red cell sizeKnown mechanism

    As this rises, Red cell size rises with it

    Short of iron, your body builds smaller red cells rather than fewer of them. So the average cell size drops as your stores run down.

  • Haemoglobin per cellKnown mechanism

    As this rises, Haemoglobin per cell rises with it

    Smaller cells hold less oxygen pigment each. So the pigment per cell falls in step with your iron stores, for the same reason.

  • Red cell size spreadObserved association

    As this rises, Red cell size spread falls as it rises

    As iron runs out, the newest cells come out smaller than the ones already circulating. Mixed sizes widen the spread, often before haemoglobin has moved at all.

  • hs-CRP can make it misleading

    Ferritin doubles as an inflammation protein. So a healthy-looking ferritin drawn during an illness cannot prove your iron stores are actually full.

  • ESR, the settling rateObserved association

    ESR can make it misleading

    A raised settling rate is signalling the same inflammation from a slower angle. It is a second reason to repeat the ferritin once you are properly well.

Common questions

What does Serum Ferritin measure?

The protein that holds your reserve iron, so its level reflects how much iron you have banked. Empties long before haemoglobin falls, which is why low ferritin explains fatigue and hair loss in someone who is not yet anaemic.

What does a high Ferritin result usually mean?

Can rise with inflammation or liver strain, not only with iron overload - read it with hs-CRP.

What does a low Ferritin result usually mean?

Your iron reserve is running down, usually before haemoglobin drops.

What is the usual reference range for Ferritin?

A broad adult reference band is 30–400 ng/mL. For women the band is 15–150 ng/mL. Labs differ, so read your result against the band printed on your own report.

Educational only, not a diagnosis. A single number means little without your history and the rest of your panel, so discuss your own results with your physician.

Typical adult reference band

Men
30–400 ng/mL
Women
15–150 ng/mL

Labs differ. The band printed on your own report is the one that applies to your result.

Reported in ng/mL, µg/L

Ageing relevance

4/5

A strong independent predictor of illness and mortality in large cohorts.

Indian reference data

Published data on this marker in Indian adults: NFHS-5; WHO 2020 ferritin guidelines.

Worth knowing

It doubles as an inflammation protein, so it climbs during any illness whether or not your iron stores are full.

Have a report with this marker on it? Read it in context.

Upload it to Oraia, our health-intelligence tool, for a plain-language read of your markers that a Genoryx doctor can review.

Your biological age is a number you can measure.

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