NAD+ IV Therapy: The Science Behind Cellular Energy

The Molecule Behind Cellular Energy

NAD+ (nicotinamide adenine dinucleotide) is not a vitamin, a supplement, or a drug. It is a coenzyme present in every living cell, essential for converting food into energy, repairing damaged DNA, activating sirtuins (the longevity genes), and maintaining cellular communication.

The problem: NAD+ levels decline with age. Research published in Cell Metabolism shows that by age 60, most people have roughly half the NAD+ they had at 20. This decline contributes to mitochondrial dysfunction, impaired DNA repair, chronic inflammation, and metabolic slowdown — the hallmarks of aging at the cellular level.

Why IV Instead of Oral?

Oral NAD+ precursors (NMN, NR) have gained popularity, but bioavailability is limited by the digestive system. IV NAD+ bypasses the gut entirely, delivering the molecule directly into the bloodstream at 100% bioavailability. A typical session delivers 250-500mg over 2-4 hours.

What Does the Evidence Say?

The animal evidence is compelling: NAD+ restoration extends lifespan in mice, improves mitochondrial function, and reverses age-related tissue damage. Human evidence is still emerging — clinical trials are showing improvements in muscle function, cognitive performance, and inflammatory markers, but long-term longevity data in humans is not yet available.

We believe in honest evidence framing: NAD+ is one of the most promising molecules in longevity science, backed by strong mechanistic data and encouraging early human results. It is not a miracle cure, and we never position it as one.

Our longevity physician can assess whether NAD+ therapy is appropriate based on your biomarker profile, health goals, and current health status. Book a consultation to discuss your options.